Drew Barrymore was just 7 when she charmed the world as Gertie in Steven Spielberg's E.T. the Extra-Terrestrial (1982). She came from Hollywood royalty, too: the Barrymores had been acting for generations.
Her teenage years were famously rocky, but she rebuilt her career in the '90s with hits like The Wedding Singer. She also produced the Charlie's Angels films through her own company, and in 2020 she launched The Drew Barrymore Show.